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Image Search Results
Journal: Vaccine
Article Title: Strong immunogenicity & protection in mice with PlaCCine: A COVID-19 DNA vaccine formulated with a functional polymer.
doi: 10.1016/j.vaccine.2024.01.065
Figure Lengend Snippet: Fig. 4. Cellular immune response to pVAC15, 16 and 17 at 16 months post vaccination. (A) Detection of IFN-γ responses in Balb/c mice post administration of DNA vaccine pVAC15, 16 and 17. T cell responses were measured by IFN-γ ELISpot in spleenocytes stimulated for 20 h with overlapping peptide pools spanning SARS-CoV-2 spike, S1 region. The phenotype of the cellular response was measured by flow cytometry. (C) CD4 and (D) CD8 T cells expressing IFN-γ and TNF-a following in vitro spike stimulation are presented. *P < 0.05, **P < 0.01, **** P < 0.0001.
Article Snippet: Each spleen was then stimulated with
Techniques: Enzyme-linked Immunospot, Flow Cytometry, Expressing, In Vitro